Publikationen
2024
Graf J, Schulz H, Wehland M, Corydon TJ, Sahana J, Abdelfattah F, Wuest SL, Egli M, Krüger M, Kraus A, Wise PM, Infanger M, Grimm D. Omics Studies of Tumor Cells under Microgravity Conditions. Int J Mol Sci. 2024 Jan 11;25(2):926. doi: 10.3390/ijms25020926
2023
Steinwerth P, Bertrand J, Sandt V, Marchal S, Sahana J, Bollmann M, Schulz H, Kopp S, Grimm D, Wehland M. Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor. Biomolecules. 2023 Dec 24;14(1):25. doi: 10.3390/biom14010025.
Cortés-Sánchez JL, Melnik D, Sandt V, Kahlert S, Marchal S, Johnson IRD, Calvaruso M, Liemersdorf C, Wuest SL, Grimm D, Krüger M. Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine. Cells. 2023 Nov 20;12(22):2665. doi: 10.3390/cells12222665.
Cialdai F, Brown AM, Baumann CW, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, Bottai D, Buchheim JI, Calvaruso M, Carnero-Diaz E, Castiglioni S, Cavalieri D, Ceccarelli G, Choukér A, Ciofani G, Coppola G, Cusella G, Degl'Innocenti A, Desaphy JF, Frippiat JP, Gelinsky M, Genchi G, Grano M, Grimm D, Guignandon A, Hahn C, Hatton J, Herranz R, Hellweg CE, Iorio CS, Karapantsios T, van Loon J, Lulli M, Maier J, Malda J, Mamaca E, Morbidelli L, van Ombergen A, Osterman A, Ovsianikov A, Pampaloni F, Pavezlorie E, Pereda-Campos V, Przybyla C, Puhl C, Rettberg P, Risaliti C, Rizzo AM, Robson-Brown K, Rossi L, Russo G, Salvetti A, Santucci D, Sperl M, Strollo F, Tabury K, Tavella S, Thielemann C, Willaert R, Szewczyk NJ, Monici M. How do gravity alterations affect animal and human systems at a cellular/tissue level? NPJ Microgravity. 2023 Oct 21;9(1):84. doi: 10.1038/s41526-023-00330-y.
Grimm D. Recent Advances in Breast Cancer Research. Int J Mol Sci. 2023 Jul 26;24(15):11990. doi: 10.3390/ijms241511990.
Sahana U, Wehland M, Simonsen U, Schulz H, Grimm D. A Systematic Review of the Effect of Vericiguat on Patients with Heart Failure. Int J Mol Sci. 2023 Jul 23;24(14):11826. doi: 10.3390/ijms241411826.
Miranda S, Marchal S, Cumps L, Dierckx J, Krüger M, Grimm D, Baatout S, Tabury K, Baselet B. A Dusty Road for Astronauts. Biomedicines. 2023 Jul 6;11(7):1921. doi: 10.3390/biomedicines11071921.
Corydon TJ, Schulz H, Richter P, Strauch SM, Böhmer M, Ricciardi DA, Wehland M, Krüger M, Erzinger GS, Lebert M, Infanger M, Wise PM, Grimm D. Current Knowledge about the Impact of Microgravity on Gene Regulation. Cells. 2023 Mar 29;12(7):1043. doi: 10.3390/cells12071043.
Melnik D, Cortés-Sánchez JL, Sandt V, Kahlert S, Kopp S, Grimm D, Krüger M. Dexamethasone Selectively Inhibits Detachment of Metastatic Thyroid Cancer Cells during Random Positioning. Cancers (Basel). 2023 Mar 7;15(6):1641. doi: 10.3390/cancers15061641.
Jensen NS, Wehland M, Wise PM, Grimm D. Latest Knowledge on the Role of Vitamin D in Hypertension. Int J Mol Sci. 2023 Feb 28;24(5):4679. doi: 10.3390/ijms24054679.
Jokšienė J, Sahana J, Wehland M, Schulz H, Cortés-Sánchez JL, Prat-Duran J, Grimm D, Simonsen U. Effects of High Glucose on Human Endothelial Cells Exposed to Simulated Microgravity. Biomolecules. 2023 Jan 17;13(2):189. doi: 10.3390/biom13020189.
Højer Wang L, Wehland M, Wise PM, Infanger M, Grimm D, Kreissl MC. Cabozantinib, Vandetanib, Pralsetinib and Selpercatinib as Treatment for Progressed Medullary Thyroid Cancer with a Main Focus on Hypertension as Adverse Effect. Int J Mol Sci. 2023 Jan 24;24(3):2312. doi: 10.3390/ijms24032312.
Sahana J, Cortés-Sánchez JL, Sandt V, Melnik D, Corydon TJ, Schulz H, Cai Z, Evert K, Grimm D, Wehland M. Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells. Int J Mol Sci. 2023 Jan 7;24(2):1181. doi: 10.3390/ijms24021181.
2022
Wise PM, Sahana J, Neviani P, Corydon TJ, Schulz H, Wehland M, Infanger M, Grimm D. Prolonged Exposure to Simulated Microgravity Changes Release of Small Extracellular Vesicle in Breast Cancer Cells. Int J Mol Sci. 2022 Dec 17;23(24):16095. doi: 10.3390/ijms232416095. PMID:
Grimm D, Hemmersbach R. Translation from Microgravity Research to Earth Application. Int J Mol Sci. 2022 Sep 20;23(19):10995. doi: 10.3390/ijms231910995.
Baran R, Wehland M, Schulz H, Heer M, Infanger M, Grimm D. Microgravity-Related Changes in Bone Density and Treatment Options: A Systematic Review. Int J Mol Sci. 2022 Aug 3;23(15):8650. doi: 10.3390/ijms23158650.
Schulz H, Dietrichs D, Wehland M, Corydon TJ, Hemmersbach R, Liemersdorf C, Melnik D, Hübner N, Saar K, Infanger M, Grimm D. In Prostate Cancer Cells Cytokines Are Early Responders to Gravitational Changes Occurring in Parabolic Flights. Int J Mol Sci. 2022 Jul 17;23(14):7876. doi: 10.3390/ijms23147876.
Grimm D. Recent Advances in Thyroid Cancer Research. Int J Mol Sci. 2022 Apr 22;23(9):4631. doi: 10.3390/ijms23094631.
Grimm D. Microgravity and Space Medicine 2.0. Int J Mol Sci. 2022 Apr 18;23(8):4456. doi: 10.3390/ijms23084456.
Grimm D, Schulz H, Krüger M, Cortés-Sánchez JL, Egli M, Kraus A, Sahana J, Corydon TJ, Hemmersbach R, Wise PM, Infanger M, Wehland M. The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model. Int J Mol Sci. 2022 Mar 12;23(6):3073.
Jing Wang, Kirsten Harth, Dmitry Puzyrev, Ralf Stannarius.
The effect of obstacles near a silo outlet on the discharge of soft spheres
New J. Phys. 24 093010 (2022)
Torsten Trittel, Christoph Klopp, Kirsten Harth, Ralf Stannarius
Stability and Rupture of Liquid Crystal Bridges Under Microgravity
Crystals 12 1092 (2022)
Amine Missaoui, Kirsten Harth, Torsten Trittel, Christoph Klopp, Ralf Stannarius, Emmanuelle Lacaze
Shape instabilities of islands in smectic films under lateral compression
Soft Matter, 18 3193 (2022)
Christoph Klopp, Torsten Trittel, Kirsten Harth, Ralf Stannarius,
Smectic free-standing films under fast lateral compression .
Soft Matter, 18 146 (2022)
Dietrichs D, Grimm D, Sahana J, Melnik D, Corydon TJ, Wehland M, Krüger M, Vermeesen R, Baselet B, Baatout S, Hybel TE, Kahlert S, Schulz H, Infanger M, Kopp S.
Three-dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity.
Front Cell Dev Biol. 2022 in press.
Norre T, Grimm D, Simonsen U.
Sacubitril/valsartan, sodium-glucose cotransporter 2 inhibitors, and vericiguat for congestive heart failure therapy.
Basic Clin Pharmacol Toxicol. 2022 Apr;130(4):425-438. doi: 10.1111/bcpt.13714.
Tsortouktzidis D, Tröscher AR, Schulz H, Opitz T, Schoch S, Becker AJ, van Loo KMJ. A Versatile
Clustered Regularly Interspaced Palindromic Repeats Toolbox to Study Neurological CaV3.2 Channelopathies by Promoter-Mediated Transcription Control.
Front Mol Neurosci. 2022 Jan 6;14:667143.
Hansen E, Grimm D, Wehland M.
Current Knowledge about the New Drug Firibastat in Arterial Hypertension.
International Journal of Molecular Sciences. 2022; 23(3):1459.
Schulz H, Strauch SM, Richter P, Wehland M, Krüger M, Sahana J, Corydon TJ, Wise P, Baran R, Lebert M, Grimm D.
Latest knowledge about changes in the proteome in microgravity.
Expert Rev Proteomics. 2022 Jan;19(1):43-59. doi: 10.1080/14789450.2022.2030711.
2021
Pavel V. Dolganov et al.
Transient hexagonal structures in sheared emulsions of isotropic inclusions on smectic bubbles in microgravity conditions
Scientific Rep. 11 19144 (2021).
Dmitry Puzyrev et al.
Visual analysis of density and velocity proles indense 3D granular gases.
Scientific Rep. 11 10621, (2021).
M. Noirhomme et al.,
Particle Dynamics at the Onset of the Granular Gas-Liquid Transition.
Phys. Rev. Lett. 126 128002 (2022)
Amine Missaoui, , Emmanuelle Lacaze, Alexey Eremin, and Ralf Stannarius,
Observation of backow during the anihilation of topologocal defects in freely suspended smectic films
Crystals, 11 430, (2021).
Dmitry Puzyrev, Raul Cruz Hidalgo, David Fischer, Kirsten Harth, Torsten Trittel, and Ralf Stannarius
Cluster dynamics in dense granular gases of rod-like particles
EPJ Web of Conferences, 249 04004 (2021).
Mahdieh Mohammadi, Kirsten Harth, Dmitry Puzyrev, Torsten Trittel, Tina Hanselka, and Ralf Stannarius
Mechanically driven active and passive grains as models for egress dynamics
EPJ Web of Conferences, 249 03016 (2021).
Tivadar Pongo, Dmitry Puzyrev, Kirsten Harth, Ralf Stannarius, and Raul Cruz Hidalgo
Continuously heated granular gas of elongated particles
EPJ Web of Conferences, 249 04003 (2021).
Baran R, Marchal S, Garcia Campos S, Rehnberg E, Tabury K, Baselet B, Wehland M, Grimm D, Baatout S.
The Cardiovascular System in Space: Focus on In Vivo and In Vitro Studies. Biomedicines. 2021 Dec 28;10(1):59.
Cortés-Sánchez JL, Callant J, Krüger M, Sahana J, Kraus A, Baselet B, Infanger M, Baatout S, Grimm D. Cancer Studies under Space Conditions: Finding Answers Abroad. Biomedicines. 2021 Dec 23;10(1):25.
Kruppa P, Georgiou I, Schmidt J, Infanger M, Ghods M. A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction. Plast Reconstr Surg. 2022 Jan 24.
Fanini F, Bandini E, Plousiou M, Carloni S, Wise P, Neviani P, Murtadha M, Foca F, Fabbri F, Vannini I, Fabbri M. MicroRNA-16 Restores Sensitivity to Tyrosine Kinase Inhibitors and Outperforms MEK Inhibitors in KRAS-Mutated Non-Small Cell Lung Cancer. Int J Mol Sci. 2021 Dec 12;22(24):13357.
Wise PM, Neviani P, Riwaldt S, Corydon TJ, Wehland M, Braun M, Krüger M, Infanger M, Grimm D. Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space. Int J Mol Sci. 2021 Nov 27;22(23):12841.
Kaae AC, Kreissl MC, Krüger M, Infanger M, Grimm D, Wehland M. Kinase-Inhibitors in Iodine-Refractory Differentiated Thyroid Cancer-Focus on Occurrence, Mechanisms, and Management of Treatment-Related Hypertension. Int J Mol Sci. 2021 Nov 12;22(22):12217.
Moroni L, Tabury K, Stenuit H, Grimm D, Baatout S, Mironov V. What can biofabrication do for space and what can space do for biofabrication? Trends Biotechnol. 2021 Sep 17:S0167-7799(21)00195-5.
Melnik D, Krüger M, Schulz H, Kopp S, Wehland M, Bauer J, Baselet B, Vermeesen R, Baatout S, Corydon TJ, Infanger M, Grimm D. The CellBox-2 Mission to the International Space Station: Thyroid Cancer Cells in Space. International Journal of Molecular Sciences. 2021; 22(16):8777.
Bauer J, Gombocz E, Schulz H, Hauslage J, Grimm D. Interaction Network Provides Clues on the Role of BCAR1 in Cellular Response to Changes in Gravity. Computation. 2021; 9(8):81.
Sahana J, Corydon TJ, Wehland M, Krüger M, Kopp S, Melnik D, Kahlert S, Relja B, Infanger M, Grimm D. Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine. Front Cell Dev Biol. 2021 Jun 30;9:672098.
Riwaldt S, Corydon TJ, Pantalone D, Sahana J, Wise P, Wehland M, Krüger M, Melnik D, Kopp S, Infanger M, Grimm D. Role of Apoptosis in Wound Healing and Apoptosis Alterations in Microgravity. Front Bioeng Biotechnol. 2021 Jun 17;9:679650.
Grimm D. Microgravity and Space Medicine. Int J Mol Sci. 2021 Jun 22;22(13):6697.
Ravichandran B, Grimm D, Krüger M, Kopp S, Infanger M, Wehland M. SARS-CoV-2 and hypertension. Physiol Rep. 2021 Jun;9(11):e14800.
Grimm D. Cell and Molecular Biology of Thyroid Disorders 2.0. Int J Mol Sci. 2021 Feb 17;22(4):1990.
Wise PM, Neviani P, Riwaldt S, Corydon TJ, Wehland M, Braun M, Krüger M, Infanger M, Grimm D. Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space. Int J Mol Sci. 2021 Feb 21;22(4):2132.
Baran R, Grimm D, Infanger M, Wehland M. The Effect of Continuous Positive Airway Pressure Therapy on Obstructive Sleep Apnea-Related Hypertension. Int J Mol Sci. 2021 Feb 25;22(5):230
Tsortouktzidis D, Schulz H, Hamed M, Vatter H, Surges R, Schoch S, Sander T, Becker AJ, van Loo KMJ. Gene expression analysis in epileptic hippocampi reveals a promoter haplotype conferring reduced aldehyde dehydrogenase 5a1 expression and responsiveness. Epilepsia. 2021 Jan;62(1):e29-e34.
Krüger M, Richter P, Strauch SM. Natural Products in Modern Biology: Ancient Wisdom for Today's Challenges. Biology (Basel). 2021 Apr 25;10(5):369.
Eschborn J, Kruppa P, Georgiou I, Infanger M, Ghods M. Long-term Results After Autologous Fat Transfer for Treatment of Chronic Lower Extremity Wounds. Int J Low Extrem Wounds. 2021 Jun 28:15347346211027684. doi: 10.1177/15347346211027684. Epub ahead of print.
2020
Wehland M, Steinwerth P, Aleshcheva G, Sahana J, Hemmersbach R, Lützenberg R, Kopp S, Infanger M, Grimm D. Tissue Engineering of Cartilage Using a Random Positioning Machine. Int J Mol Sci. 2020 Dec 16;21(24):9596.
Grimm D, Bauer J, Wise P, Krüger M, Simonsen U, Wehland M, Infanger M, Corydon TJ. The role of SOX family members in solid tumours and metastasis. Semin Cancer Biol. 2020 Dec;67(Pt 1):122-153.
Prasad B, Grimm D, Strauch SM, Erzinger GS, Corydon TJ, Lebert M, Magnusson NE, Infanger M, Richter P, Krüger M. Influence of Microgravity on Apoptosis in Cells, Tissues, and Other Systems In Vivo and In Vitro. Int J Mol Sci. 2020 Dec 9;21(24):9373.
Johnson IRD, Nguyen CT, Wise P, Grimm D. Implications of Altered Endosome and Lysosome Biology in Space Environments. Int J Mol Sci. 2020 Nov 2;21(21):8205.
Nassef MZ, Melnik D, Kopp S, Sahana J, Infanger M, Lützenberg R, Relja B, Wehland M, Grimm D, Krüger M. Breast Cancer Cells in Microgravity: New Aspects for Cancer Research. Int J Mol Sci. 2020 Oct 5;21(19):7345.
Krüger M, Kopp S, Wehland M, Corydon TJ, Grimm D. Science between Bioreactors and Space Research-Response to Comments by Joseph J. Bevelacqua et al. on "Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity". Cells. 2020 Jul 23;9(8):1763.
Prasad B, Richter P, Vadakedath N, Mancinelli R, Krüger M, Strauch SM, Grimm D, Darriet P, Chapel JP, Cohen J, Lebert M. Exploration of space to achieve scientific breakthroughs. Biotechnol Adv. 2020 Nov 1;43:107572.
Grimm D, Wehland M, Corydon TJ, Richter P, Prasad B, Bauer J, Egli M, Kopp S, Lebert M, Krüger M. The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells. Stem Cells Transl Med. 2020 Aug;9(8):882-894.
Enevoldsen FC, Sahana J, Wehland M, Grimm D, Infanger M, Krüger M. Endothelin Receptor Antagonists: Status Quo and Future Perspectives for Targeted Therapy. J Clin Med. 2020 Mar 18;9(3):824.
Bauer TJ, Gombocz E, Wehland M, Bauer J, Infanger M, Grimm D. Insight in Adhesion Protein Sialylation and Microgravity Dependent Cell Adhesion-An Omics Network Approach. Int J Mol Sci. 2020 Mar 4;21(5):1749.
Wehland M, Simonsen U, Buus NH, Krüger M, Grimm D. An evaluation of the fixed dose combination sacubitril/valsartan for the treatment of arterial hypertension. Expert Opin Pharmacother. 2020 Jul;21(10):1133-1143.
Hybel TE, Dietrichs D, Sahana J, Corydon TJ, Nassef MZ, Wehland M, Krüger M, Magnusson NE, Bauer J, Utpatel K, Infanger M, Grimm D, Kopp S. Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells. Int J Mol Sci. 2020 Feb 13;21(4):1263.
Melnik D, Sahana J, Corydon TJ, Kopp S, Nassef MZ, Wehland M, Infanger M, Grimm D, Krüger M. Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity. Cells. 2020 Feb 5;9(2):367
Povlsen AL, Grimm D, Wehland M, Infanger M, Krüger M. The Vasoactive Mas Receptor in Essential Hypertension. J Clin Med. 2020 Jan 18;9(1):267.
Wolking S, Schulz H, Nies AT, McCormack M, Schaeffeler E, Auce P, Avbersek A, Becker F, Klein KM, Krenn M, Møller RS, Nikanorova M, Weckhuysen S, Consortium E, Cavalleri GL, Delanty N, Depondt C, Johnson MR, Koeleman BP, Kunz WS, Marson AG, Sander JW, Sills GJ, Striano P, Zara F, Zimprich F, Weber YG, Krause R, Sisodiya S, Schwab M, Sander T, Lerche H. Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study. Pharmacogenomics. 2020 Apr;21(5):325-335.
Dieteren S, Franz N, Köhler K, Nowak A, Ehnert S, Surov A, Krüger M, Marzi I, Wagner N, Relja B. Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock. Front Med (Lausanne). 2020 Oct 2;7:562904.
Hirsch P, Infanger M, Kraus A. A case of upper lip necrosis after cosmetic injection of hyaluronic acid soft-tissue filler-Does capillary infarction play a role in the development of vascular compromise, and what are the implications? J Cosmet Dermatol. 2020 Jun;19(6):1316-1320.
Strube F, Infanger M, Wehland M, Delvinioti X, Romswinkel A, Dietz C, Kraus A. Alteration of Cytoskeleton Morphology and Gene Expression in Human Breast Cancer Cells under Simulated Microgravity. Cell J. 2020 Apr;22(1):106-114.
Schuchardt M, Siegel NV, Babic M, Reshetnik A, Lützenberg R, Zidek W, van der Giet M, Tölle M. A Novel Long-Term ex vivo Model for Studying Vascular Calcification Pathogenesis: The Rat Isolated-Perfused Aorta. J Vasc Res. 2020;57(1):46-52.
2019
Legarth C, Grimm D, Krüger M, Infanger M, Wehland M. Potential Beneficial Effects of Vitamin D in Coronary Artery Disease. Nutrients. 2019 Dec 30;12(1):99.
Ancker OV, Krüger M, Wehland M, Infanger M, Grimm D. Multikinase Inhibitor Treatment in Thyroid Cancer. Int J Mol Sci. 2019 Dec 18;21(1):10.
Nassef MZ, Kopp S, Melnik D, Corydon TJ, Sahana J, Krüger M, Wehland M, Bauer TJ, Liemersdorf C, Hemmersbach R, Infanger M, Grimm D. Short-term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells. Int J Mol Sci 2019;20(22):5730.
Bauer TJ, Gombocz E, Krüger M, Sahana J, Corydon TJ, Bauer J, Infanger M, Grimm D. Augmenting cancer cell proteomics with cellular images – A semantic approach to understand focal adhesion. J Biomed Inform 2019;100:103320.
Deutch MR, Grimm D, Wehland M, Infanger M, Krüger M. Bioactive Candy: Effects of Licorice on the Cardiovascular System. Foods 2019;8(10):495.
Grimm D. Guest Edited Collection: Gravitational biology and space medicine. Sci Rep.2019;9(1):14399.
Lützenberg R, Wehland M, Solano K, Nassef MZ, Buken C, Melnik D, Bauer J, Kopp S, Krüger M, Riwaldt S, Hemmersbach R, Schulz H, Infanger M, Grimm D. Beneficial Effects of Low Frequency Vibration on Human Chondrocytes in Vitro. Cell Physiol 2019;53:623-637.
Bæk Møller N, Budolfsen C, Grimm D, Krüger M, Infanger M, Wehland M, Magnusson NE. Drug-Induced Hypertension Caused by Multikinase Inhibitors (Sorafenib, Sunitinib, Lenvatinib and Axitinib) in Renal Cell Carcinoma Treatment. Int J Mol Sci 2019;20(19):4712.
Lindegaard Pedersen M, Krüger M, Grimm D, Infanger M, Wehland M. The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension. Basic Clin Pharmacol Toxicol. 2019 Aug 12.
Buken C, Sahana J, Corydon TJ, Melnik D, Bauer J, Wehland M, Krüger M, Balk S, Abuagela N, Infanger M, Grimm D. Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity. Sci Rep 2019;9(1):11882.
Khalaf D, Krüger M, Wehland M, Infanger M, Grimm D. The Effects of Oral LArginine and L-Citrulline Supplementation on Blood Pressure. Nutrients 2019;11(7):1679.
Nassef MZ, Kopp S, Wehland M, Melnik D, Sahana J, Krüger M, Corydon TJ, Oltmann H, Schmitz B, Schütte A, Bauer, TJ, Infanger M, Grimm D. Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells. Int J Mol Sci, 2019;20(13):3156.
Toxvig AK, Wehland M, Grimm D, Infanger M, Krüger M. A Focus on Riociguat in the Treatment of Pulmonary Arterial Hypertension. Basic Clin Pharmacol Toxicol 2019;125:202-214.
Grimm D. Cell and Molecular Biology of Thyroid Disorders. Int J Mol Sci. 2019;20(12):2895.
Krüger M, Melnik D, Kopp S, Buken C, Sahana J, Bauer J, Wehland M, Hemmersbach R, Corydon TJ, Infanger M, Grimm D. Fighting Thyroid Cancer with Microgravity Research. Int J Mol Sci 2019;20(10):2553.
Olawi N, Krüger M, Grimm D, Infanger M, Wehland M. Nebivolol in the Treatment of Arterial Hypertension. Basic Clin Pharmacol Toxicol 2019;125:189-201.
Krüger M, Pietsch J, Bauer J, Kopp S, Carvalho DTO, Baatout S, Moreels M, Melnik D, Wehland M, Egli M, Sahana J, Kobberø SD, Corydon TJ, Nebuloni S, Gass S, Evert M, Infanger M, Grimm D. Growth of Endothelial Cells in Space and in Simulated Microgravity – A Comparison on the Secretory Level. Cell Physiol Biochem 2019;52(5):1039-1060.
Krüger M, Kopp S, Wehland M, Bauer J, Baatout S, Moreels M, Egli M, Corydon TJ, Infanger M, Grimm D. Growing blood vessels in space: Preparation studies of the SPHEROIDS project using related ground-based studies. Acta Astronaut 2019;159:267-272.
Mann V, Grimm D, Corydon TJ, Krüger M, Wehland M, Riwaldt S, Sahana J, Kopp S, Bauer J, Reseland JE, Infanger M, Lian AM, Okoro E, Sundaresan A. Changes in Human Foetal Osteoblasts Exposed to the Random Positioning Machine and Bone Construct Tissue Engineering. Int J Mol Sci 2019; 20(6):1357.
Budolfsen C, Faber J, Grimm D, Krüger M, Bauer J, Wehland M, Infanger M, Magnusson NE. Tyrosine Kinase Inhibitor-Induced Hypertension: Role of Hypertension as a Biomarker in Cancer Treatment. Curr Vasc Pharmacol 2019;17(6):618-634.
Strauch SM, Grimm D, Corydon TJ, Krüger M, Bauer J, Lebert M, Wise P, Infanger M, Richter P. Current knowledge about the impact of microgravity on the proteome. Expert Rev Proteomics 2019;16(1):1-12.
Gorvin CM, Loh NY, Stechman MJ, Falcone S, Hannan FM, Ahmad BN, Piret SE, Reed AA, Jeyabalan J, Leo P, Marshall M, Sethi S, Bass P, Roberts I, Sanderson J, Wells S, Hough TA, Bentley L, Christie PT, Simon MM, Mallon AM, Schulz H, Cox RD, Brown MA, Huebner N, Brown SD, Thakker RV. Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis. J Bone Miner Res. 2019 Jul;34(7):1324-1335.
Prüss H, Gessner G, Heinemann SH, Rüschendorf F, Ruppert AK, Schulz H, Sander T, Rimpau W. Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel KCNQ1 Loss-of-Function Mutation. Front Neurol. 2019 Jun 25;10:648.
Schulz H, Ruppert AK, Zara F, Madia F, Iacomino M, S Vari M, Balagura G, Minetti C, Striano P, Bianchi A, Marini C, Guerrini R, Weber YG, Becker F, Lerche H, Kapser C, Schankin CJ, Kunz WS, Møller RS, Oliver KL, Bellows ST, Mullen SA, Berkovic SF, Scheffer IE, Caglayan H, Ozbek U, Hoffmann P, Schramm S, Tsortouktzidis D, Becker AJ, Sander T. No evidence for a BRD2 promoter hypermethylation in blood leukocytes of Europeans with juvenile myoclonic epilepsy. Epilepsia. 2019 May;60(5):e31-e36.
Gorvin CM, Ahmad BN, Stechman MJ, Loh NY, Hough TA, Leo P, Marshall M, Sethi S, Bentley L, Piret SE, Reed A, Jeyabalan J, Christie PT, Wells S, Simon MM, Mallon AM, Schulz H, Huebner N, Brown MA, Cox RD, Brown SD, Thakker RV. An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice. J Bone Miner Res. 2019 Mar;34(3):497-507.
Krüger J, Richter P, Stoltze J, Strauch SM, Krüger M, Daiker V, Prasad B, Sonnewald S, Reid S, Lebert M. Changes of Gene Expression in Euglena gracilis Obtained During the 29th DLR Parabolic Flight Campaign. Sci Rep. 2019 Oct 3;9(1):14260.
Richter P, Krüger M, Prasad B, Gastiger S, Bodenschatz M, Wieder F, Burkovski A, Geißdörfer W, Lebert M, Strauch SM. Using Colistin as a Trojan Horse: Inactivation of Gram-Negative Bacteria with Chlorophyllin. Antibiotics (Basel). 2019 Sep 20;8(4):158.
Krüger M, Richter P, Strauch SM, Nasir A, Burkovski A, Antunes CA, Meißgeier T, Schlücker E, Schwab S, Lebert M. What an Escherichia coli Mutant Can Teach Us About the Antibacterial Effect of Chlorophyllin. Microorganisms. 2019 Feb 22;7(2):59.
Kraus A, Infanger M, Meyer F. What does a (general and abdominal) surgeon need to know on plastic surgery? Pol Przegl Chir. 2019 Jun 6;91(5):41-50.
Romswinkel A, Infanger M, Dietz C, Strube F, Kraus A. The Role of C-X-C Chemokine Receptor Type 4 (CXCR4) in Cell Adherence and Spheroid Formation of Human Ewing's Sarcoma Cells under Simulated Microgravity. Int J Mol Sci. 2019 Dec 2;20(23):6073.
Dietz C, Infanger M, Romswinkel A, Strube F, Kraus A. Apoptosis Induction and Alteration of Cell Adherence in Human Lung Cancer Cells under Simulated Microgravity. Int J Mol Sci. 2019 Jul 23;20(14):3601. doi: 10.3390/ijms20143601.
Strube F, Infanger M, Dietz C, Romswinkel A, Kraus A Short Term Effects of Simulated Microgravity on Morphology and Gene Expression in Human Breast Cancer Cells. Physiol Int. 2019 Dec 1;106(4)
2018
Kopp S, Krüger M, Bauer J, Wehland M, Corydon TJ, Sahana J, Nassef MZ, Melnik D, Bauer TJ, Schulz H, Schütte A, Schmitz B, Oltmann H, Feldmann S, Infanger M, Grimm D. Microgravity Affects Thyroid Cancer Cells during the TEXUS-53 Mission Stronger than Hypergravity. Int J Mol Sci. 2018;19(12). pii: 4001.
Bauer J, Cohly HHP, Sahana J, Grimm D. Preparative enrichment of human tissue cells capable to change a site of growth in vitro or in vivo - Recent developments. Prep Biochem Biotechnol. 2018 Nov 5:1-7.
Milling RV, Grimm D, Krüger M, Grosse J, Kopp S, Bauer J, Infanger M, Wehland M. Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effe1cts on Hypertension. Int J Mol Sci. 2018 Oct 20;19(10). pii: E3258.
Bauer J, Wehland M, Infanger M, Grimm D, Gombocz E. Semantic Analysis of Posttranslational Modification of Proteins Accumulated in Thyroid Cancer Cells Exposed to Simulated Microgravity. Int J Mol Sci. 2018 Aug 1;19(8). pii: E2257.
Lützenberg R, Solano K, Buken C, Sahana J, Riwaldt S, Kopp S, Krüger M, Schulz H, Saar K, Huebner N, Hemmersbach R, Bauer J, Infanger M, Grimm D, Wehland M. Pathway Analysis Hints Towards Beneficial Effects of Long-Term Vibration on HumanC hondrocytes. Cell Physiol Biochem. 2018; 47(4):1729-1741.
Sahana J, Nassef MZ, Wehland M, Kopp S, Krüger M, Corydon TJ, Infanger M, Bauer J, Grimm D. Decreased E-Cadherin in MCF7 Human Breast Cancer Cells Forming Multicellular Spheroids Exposed to Simulated Microgravity. Proteomics. 2018; 18(13):e1800015.
Kopp S, Krüger M, Feldmann S, Oltmann H, Schütte A, Schmitz B, Bauer J, Schulz H, Saar K, Huebner N, Wehland M, Nassef MZ, Melnik D, Meltendorf S, Infanger M, Grimm D. Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project. Sci Rep. 2018; 8(1):10355
Bedan M, Grimm D, Wehland M, Simonsen U, Infanger M, Krüger M. A Focus on Macitentan in the Treatment of Pulmonary Arterial Hypertension. Basic Clin Pharmacol Toxicol. 2018 Aug;123(2):103-113.
Grimm D, Egli M, Krüger M, Riwaldt S, Corydon TJ, Kopp S, Wehland M, Wise P, Infanger M, Mann V, Sundaresan A. Tissue Engineering Under Microgravity Conditions-Use of Stem Cells and Specialized Cells. Stem Cells Dev. 2018 Jun 15;27(12):787-804.
Legarth C, Grimm D, Wehland M, Bauer J, Krüger M. The Impact of Vitamin D in the Treatment of Essential Hypertension. Int J Mol Sci. 2018 Feb 3;19(2). pii: E455.
Dittrich A, Grimm D, Sahana J, Bauer J, Krüger M, Infanger M, Magnusson NE. Key Proteins Involved in Spheroid Formation and Angiogenesis in Endothelial Cells After Long-Term Exposure to Simulated Microgravity. Cell Physiol Biochem. 2018;45(2):429-445.
Kopp S, Sahana J, Islam T, Petersen AG, Bauer J, Corydon TJ, Schulz H, Saar K, Huebner N, Slumstrup L, Riwaldt S, Wehland M, Infanger M, Luetzenberg R, Grimm D. The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine. Sci Rep. 2018 Jan 17;8(1):921.
Nielsen PM, Grimm D, Wehland M, Simonsen U, Krüger M. The Combination of Valsartan and Sacubitril in the Treatment of Hypertension and Heart Failure - an Update. Basic Clin Pharmacol Toxicol. 2018 Jan;122(1):9-18.
Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A. Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153.
Kraus A, Sattler D, Wehland M, Luetzenberg R, Abuagela N, Infanger M. Vascular Endothelial Growth Factor Enhances Proliferation of Human Tenocytes and Promotes Tenogenic Gene Expression. Plast Reconstr Surg. 2018 Nov;142(5):1240-1247. doi: 10.1097/PRS.0000000000004920. PMID: 30113440.
Kraus A, Infanger M, Chiapponi C, Piatek S, Zardo P, Udelnow A, Haß HJ, Meyer F. Surgical teaching at the Medical School Otto-von-Guericke University of Magdeburg - basic conceptual description. Pol Przegl Chir. 2018 May 16;90(3):37-42.
Kraus A, Luetzenberg R, Abuagela N, Hollenberg S, Infanger M. Spheroid formation and modulation of tenocyte-specific gene expression under simulated microgravity. Muscles Ligaments Tendons J. 2018 Jan 10;7(3):411-417.
2017
Bauer J, Grimm D, Gombocz E. Semantic analysis of thyroid cancer cell proteins obtained from rare research opportunities. J Biomed Inform. 2017 Dec;76:138-153.
Sørensen LM, Wehland M, Krüger M, Simonsen U, Nassef MZ, Infanger M, Grimm D. A Special Focus on Selexipag - Treatment of Pulmonary Arterial Hypertension. Curr Pharm Des. 2017;23(34):5191-5199.
Warnke E, Pietsch J, Kopp S, Bauer J, Sahana J, Wehland M, Krüger M, Hemmersbach R, Infanger M, Lützenberg R, Grimm D. Cytokine Release and Focal Adhesion Proteins in Normal Thyroid Cells Cultured on the Random Positioning Machine. Cell Physiol Biochem. 2017 Aug 30;43(1):257-270.
Bendtsen MAF, Grimm D, Bauer J, Wehland M, Wise P, Magnusson NE, Infanger M, Krüger M. Hypertension Caused by Lenvatinib and Everolimus in the Treatment of Metastatic Renal Cell Carcinoma. Int J Mol Sci. 2017 Aug 10;18(8). pii: E1736.
Grimm D. Current Knowledge in Thyroid Cancer-From Bench to Bedside. Int J Mol Sci. 2017 Jul 15;18(7). pii: E1529.
Hjermitslev M, Grimm DG, Wehland M, Simonsen U, Krüger M. Azilsartan Medoxomil, an Angiotensin II Receptor Antagonist for the Treatment of Hypertension. Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):225-233.
Thorup L, Simonsen U, Grimm D, Hedegaard ER. Ivabradine: Current and Future Treatment of Heart Failure. Basic Clin Pharmacol Toxicol. 2017 Aug;121(2):89-97.
Ancker OV, Wehland M, Bauer J, Infanger M, Grimm D. The Adverse Effect of Hypertension in the Treatment of Thyroid Cancer with Multi-Kinase Inhibitors. Int J Mol Sci. 2017 Mar 14;18(3). pii: E625.
Bauer J, Kopp S, Schlagberger EM, Grosse J, Sahana J, Riwaldt S, Wehland M, Luetzenberg R, Infanger M, Grimm D. Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine. Int J Mol Sci. 2017 Mar 3;18(3). pii: E546.
Randrup Hansen C, Grimm D, Bauer J, Wehland M, Magnusson NE. Effects and Side Effects of Using Sorafenib and Sunitinib in the Treatment of Metastatic Renal Cell Carcinoma. Int J Mol Sci. 2017 Feb 21;18(2). pii: E461.
Pietsch J, Gass S, Nebuloni S, Echegoyen D, Riwaldt S, Baake C, Bauer J, Corydon TJ, Egli M, Infanger M, Grimm D. Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - The SPHEROIDS project. Biomaterials. 2017 Apr;124:126-156.
Häder DP, Braun M, Grimm D, Hemmersbach R. Gravireceptors in eukaryotes - a comparison of case studies on the cellular level. NPJ Microgravity. 2017 Apr 28;3:13.
Albi E, Krüger M, Hemmersbach R, Lazzarini A, Cataldi S, Codini M, Beccari T, Ambesi-Impiombato FS, Curcio F. Impact of Gravity on Thyroid Cells. Int J Mol Sci. 2017 May 4;18(5):972.
Schulz H, Ruppert AK, Herms S, Wolf C, Mirza-Schreiber N, Stegle O, Czamara D, Forstner AJ, Sivalingam S, Schoch S, Moebus S, Pütz B, Hillmer A, Fricker N, Vatter H, Müller-Myhsok B, Nöthen MM, Becker AJ, Hoffmann P, Sander T, Cichon S. Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus. Nat Commun. 2017 Nov 15;8(1):1511.
Zadora J, Singh M, Herse F, Przybyl L, Haase N, Golic M, Yung HW, Huppertz B, Cartwright JE, Whitley G, Johnsen GM, Levi G, Isbruch A, Schulz H, Luft FC, Müller DN, Staff AC, Hurst LD, Dechend R, Izsvák Z. Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker. Circulation. 2017 Nov 7;136(19):1824-1839.
Akcakaya NH, Capan ÖY, Schulz H, Sander T, Caglayan SH, Yapıcı Z. De novo 8p23.1 deletion in a patient with absence epilepsy. Epileptic Disord. 2017 Jun 1;19(2):217-221.
Aggarwal A, Schulz H, Manhardt T, Bilban M, Thakker RV, Kallay E. Expression profiling of colorectal cancer cells reveals inhibition of DNA replication licensing by extracellular calcium. Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):987-996.
Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS. Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy. Free RadicBiol Med. 2017 May;106:270-277.
Järve A, Mühlstedt S, Qadri F, Nickl B, Schulz H, Hübner N, Özcelik C, Bader M. Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction. FASEB J. 2017 Feb;31(2):556-568.
2016 oder älter
Corydon TJ, Mann V, Slumstrup L, Kopp S, Sahana J, Askou AL, Magnusson NE, Echegoyen D, Bek T, Sundaresan A, Riwaldt S, Bauer J, Infanger M, Grimm D. Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity. Cell Physiol Biochem. 2016;40(1-2):1-17.
Aleshcheva G, Bauer J, Hemmersbach R, Slumstrup L, Wehland M, Infanger M, Grimm D. Scaffold-free Tissue Formation Under Real and Simulated Microgravity Conditions. Basic Clin Pharmacol Toxicol. 2016 Oct;119 Suppl 3:26-33.
Frandsen S, Kopp S, Wehland M, Pietsch J, Infanger M, Grimm D. Latest Results for Anti-Angiogenic Drugs in Cancer Treatment. Curr Pharm Des.2016;22(39):5927-5942.
Laursen R, Wehland M, Kopp S, Pietsch J, Infanger M, Grosse J, Grimm D. Effects and Role of Multikinase Inhibitors in Thyroid Cancer. Curr Pharm Des. 2016;22(39):5915-5926.
Bauer J, Bussen M, Wise P, Wehland M, Schneider S, Grimm D. Searching the literature for proteins facilitates the identification of biological processes, if advanced methods of analysis are linked: a case study on microgravity-caused changes in cells. Expert Rev Proteomics. 2016 Jul;13(7):697-705.
Kopp S, Slumstrup L, Corydon TJ, Sahana J, Aleshcheva G, Islam T, Magnusson NE, Wehland M, Bauer J, Infanger M, Grimm D. Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine. Sci Rep. 2016 May 27;6:26887.
Riwaldt S, Bauer J, Wehland M, Slumstrup L, Kopp S, Warnke E, Dittrich A, Magnusson NE, Pietsch J, Corydon TJ, Infanger M, Grimm D. Pathways Regulating Spheroid Formation of Human Follicular Thyroid Cancer Cells under Simulated Microgravity Conditions: A Genetic Approach. Int J Mol Sci. 2016 Apr 8;17(4):528.
Warnke E, Kopp S, Wehland M, Hemmersbach R, Bauer J, Pietsch J, Infanger M, Grimm D. Thyroid cells exposed to simulated microgravity conditions? Comparison of the fast rotating clinostat and the Random Positioning Machine. Microgravity Sci. Technol. 2016;28:247-260
Aleshcheva G, Bauer J, Hemmersbach R, Egli M, Wehland M, Grimm D. Tissue engineering of cartilage on ground-based facilities. Microgravity Sci. Technol. 2016;28:237-245
Bauer J, Wehland M, Pietsch J, Sickmann A, Weber G, Grimm D. Annotated gene and proteome data support recognition of interconnections between the results of different experiments in space research. Microgravity Sci. Technol. 2016;28:357-365
Wehland M, Warnke E, Frett T, Hemmersbach R, Hauslage J, Ma X, Alehcheva G, Pietsch J, Bauer J, Grimm D. The impact of microgravity and vibration on gene and protein expression of thyroid cells. Microgravity Sci. Technol. 2016;28:261-274
Andersen MB, Simonsen U, Wehland M, Pietsch J, Grimm D. LCZ696 (Valsartan/ Sacubitril)--A Possible New Treatment for Hypertension and Heart Failure. Basic Clin Pharmacol Toxicol. 2016 Jan;118(1):14-22.
Grimm D, Grosse J, Wehland M, Mann V, Reseland JE, Sundaresan A, Corydon TJ. The impact of microgravity on bone in humans. Bone. 2016 Jun;87:44-56.
Corydon TJ, Kopp S, Wehland M, Braun M, Schütte A, Mayer T, Hülsing T, Oltmann H, Schmitz B, Hemmersbach R, Grimm D. Alterations of the cytoskeleton in human cells in space proved by life-cell imaging. Sci Rep. 2016 Jan 28;6:20043.
Witzel C, Brushart TM, Koulaxouzidis G, Infanger M. Electrical Nerve Stimulation Enhances Perilesional Branching after Nerve Grafting but Fails to Increase Regeneration Speed in a Murine Model. J Reconstr Microsurg. 2016 Jul;32(6):491-7.
Magarin M, Schulz H, Thierfelder L, Drenckhahn JD. Transcriptional profiling of regenerating embryonic mouse hearts. Genom Data. 2016 Aug 12;9:145-7.
Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14.
Mannhardt I, Breckwoldt K, Letuffe-Brenière D, Schaaf S, Schulz H, Neuber C, Benzin A, Werner T, Eder A, Schulze T, Klampe B, Christ T, Hirt MN, Huebner N, Moretti A, Eschenhagen T, Hansen A. Human Engineered Heart Tissue: Analysis of Contractile Force. Stem Cell Reports. 2016 Jul 12;7(1):29-42
Przybyl L, Haase N, Golic M, Rugor J, Solano ME, Arck PC, Gauster M, Huppertz B, Emontzpohl C, Stoppe C, Bernhagen J, Leng L, Bucala R, Schulz H, Heuser A, Weedon-Fekjær MS, Johnsen GM, Peetz D, Luft FC, Staff AC, Müller DN, Dechend R, Herse F. CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia. Circ Res. 2016 Jun 24;119(1):55-68.
Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. J Am Heart Assoc. 2016 Feb 17;5(2):e002701.
Megerle K, Woon C, Kraus A, Raghavan S, Pham H, Chang JFlexor Tendon Sheath Engineering Utilizing Decellularized Porcine Pericardium. Plast Reconstr Surg. 2016 Oct;138(4):630e-41e
Riwaldt S, Bauer J, Pietsch J, Braun M, Segerer J, Schwarzwälder A, Corydon TJ, Infanger M, Grimm D. The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions. Int J Mol Sci. 2015 Nov 30;16(12):28296-310.
Kopp S, Warnke E, Wehland M, Aleshcheva G, Magnusson NE, Hemmersbach R, Corydon TJ, Bauer J, Infanger M, Grimm D. Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity. Sci Rep. 2015 Nov18;5:16691.
Svejgaard B, Wehland M, Ma X, Kopp S, Sahana J, Warnke E, Aleshcheva G, Hemmersbach R, Hauslage J, Grosse J, Bauer J, Corydon TJ, Islam T, Infanger M, Grimm D. Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat. PLoS One. 2015 Aug 14;10(8):e0135157.
Riwaldt S, Pietsch J, Sickmann A, Bauer J, Braun M, Segerer J, Schwarzwälder A, Aleshcheva G, Corydon TJ, Infanger M, Grimm D. Identification of proteins involved in inhibition of spheroid formation under microgravity. Proteomics. 2015 Sep;15(17):2945-52.
Wehland M, Aleshcheva G, Schulz H, Saar K, Hübner N, Hemmersbach R, Braun M, Ma X, Frett T, Warnke E, Riwaldt S, Pietsch J, Corydon TJ, Infanger M, Grimm D. Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers. Cell Commun Signal. 2015 Mar 20;13:18.
Fisker FY, Grimm D, Wehland M. Third-generation beta-adrenoceptor antagonists in the treatment of hypertension and heart failure. Basic Clin Pharmacol Toxicol. 2015 Jul;117(1):5-14.
Aleshcheva G, Wehland M, Sahana J, Bauer J, Corydon TJ, Hemmersbach R, Frett T, Egli M, Infanger M, Grosse J, Grimm D. Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9. FASEB J. 2015 Jun;29(6):2303-14.
Wuest SL, Richard S, Kopp S, Grimm D, Egli M. Simulated microgravity: critical review on the use of random positioning machines for mammalian cell culture. Biomed Res Int. 2015;2015:971474.
Altmann S, Damert HG, Klausenitz S, Infanger M, Kraus A. Aggressive digital papillary adenocarcinoma - a rare malignant tumor of the sweat glands: two case reports and a review of the literature. Clin Cosmet Investig Dermatol. 2015 Mar 25;8:143-6.
Herlan L, Schulz A, Schulte L, Schulz H, Hübner N, Kreutz R. Novel candidate genes for impaired nephron development in a rat model with inherited nephron deficit and albuminuria. Clin Exp Pharmacol Physiol. 2015 Oct;42(10):1051-8.
Jost KL, Bertulat B, Rapp A, Brero A, Hardt T, Domaing P, Gösele C, Schulz H, Hübner N, Cardoso MC. Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood. Epigenetics Chromatin. 2015 Sep 17;8:36.
Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas- Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, Schedl A. Alternatively spliced isoforms of WT1 control podocyte-specific gene expression. Kidney Int. 2015 Aug;88(2):321-31.
Maass PG, Aydin A, Luft FC, Schächterle C, Weise A, Stricker S, Lindschau C, Vaegler M, Qadri F, Toka HR, Schulz H, Krawitz PM, Parkhomchuk D, Hecht J, Hollfinger I, Wefeld-Neuenfeld Y, Bartels-Klein E, Mühl A, Kann M, Schuster H, Chitayat D, Bialer MG, Wienker TF, Ott J, Rittscher K, Liehr T, Jordan J, Plessis G, Tank J, Mai K, Naraghi R, Hodge R, Hopp M, Hattenbach LO, Busjahn A, Rauch A, Vandeput F, Gong M, Rüschendorf F, Hübner N, Haller H, Mundlos S, Bilginturan N, Movsesian MA, Klussmann E, Toka O, Bähring S. PDE3A mutations cause autosomal dominant hypertension with brachydactyly. Nat Genet. 2015 Jun; 47(6):647-53.
Lal D, Ruppert AK, Trucks H, Schulz H, de Kovel CG, Kasteleijn-Nolst Trenité D, Sonsma AC, Koeleman BP, Lindhout D, Weber YG, Lerche H, Kapser C, Schankin CJ, Kunz WS, Surges R, Elger CE, Gaus V, Schmitz B, Helbig I, Muhle H, Stephani U, Klein KM, Rosenow F, Neubauer BA, Reinthaler EM, Zimprich F, Feucht M, Møller RS, Hjalgrim H, De Jonghe P, Suls A, Lieb W, Franke A, Strauch K, Gieger C, Schurmann C, Schminke U, Nürnberg P; EPICURE Consortium, Sander T. Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet. 2015 May 7;11(5):e1005226.
K. Harth, T. Trittel, K. May, S. Wegner, R. Stannarius "Three-dimensional (3D) experimental realization and observation of a granular gas in microgravity" Adv. Space Res. 55 1901 (2015)
S. Dölle, K. Harth, T. John, R. Stannarius, "Impact and Embedding of Picoliter Droplets into Freely Suspended Smectic Films" Langmuir 30 12712 (2014)
K. May, K. Harth, T. Trittel, R. Stannarius "Freely floating smectic films" ChemPhysChem 15 1508 (2014)
Thiel, C.S., Tauber, S., Schütte, A., Schmitz, B., Nuesse, H., Moeller, R., Ullrich, O. "Functional Activity of Plasmid DNA after Entry into the Atmosphere of Earth Investigated by a New Biomarker Stability Assay for Ballistic Spaceflight Experiments" PLoS ONE 9(11): e112979. doi:10.1371/journal.pone.0112979 (2014)
Katrin Paulsen, Svantje Tauber, Claudia Dumrese, Ullrich, O. et al. “Regulation of ICAM-1 in Cells of the Monocyte/Macrophage System in Microgravity,” BioMed Research International, Article ID 538786, in press. (2014)
Thiel, C.S., Hauschild, S., Tauber, S., Paulsen, K., Raig, C., Raem, A., Biskup, J., Gutewort, A., Hürlimann, E., Unverdorben, F., Buttron, I., Lauber, B., Philpot, C., Lier, H., Engelmann, F., Layer, L.E., Ullrich, O. "Identification of Reference Genes in Human Myelomonocytic Cells for Gene Expression Studies in Altered Gravity" BioMed Research International, Article ID 363575, in press. (2014)
Hauschild, S., Tauber, S., Lauber, B., Thiel, C.S., Layer, L.E., Ullrich, O. "T cell regulation in microgravity – The current knowledge from in vitro experiments conducted in space, parabolic flights and ground-based facilities" Acta Astronautica 104 (2014) 365-377
Adrian, A., Schoppmann, K., Sromicki, J., Brungs, S., von der Wiesche, M., Hock, B., Kolanus, W., Hemmersbach, R., Ullrich, O. "The oxidative burst reaction in mammalian cells depends on gravity." Cell Commun Signal. 2013, 11:98
Herranz, R., Anken, R., Boonstra, J., Braun, M., Christianen, P.C.M., de Geest, M., Hauslage, J., Hilbig, R., Hill, R.J.A., Lebert, M., Medina, F.J., Vagt, N., Ullrich, O., van Loon, J.W.A., Hemmersbach, R. "Ground-based facilities for simulation of microgravity: organism-specific recommendations for their use, and recommended terminology." Astrobiology 2013, 13(1): 1-17
Tauber, S., Hauschild, S., Crescio, C., Secchi, C., Paulsen, K., Pantaleo, A., Saba, A., Buttron, I., Thiel, C.S., Cogoli, A., Pippia, P., Ullrich, O.
"Signal transduction in primary human T lymphocytes in altered gravity - results of the MASER-12 suborbital space flight mission." Cell Commun Signal. 2013, 11(1):32
Simmet, D.M., Schwarzwälder, A., Paulsen, K., Tauber, S., Engelmann, F., Thiel, C., Ullrich, O. "Biotechnology for the investigation of the monocyte-macrophage-system in microgravity and space." Recent Advances in Space Biotechnology 2013, 3, 48-63
Ullrich, O., Graf, J. "Im Auftrag für Medizin und Forschung. Spezialtransporte an Bord von Luftfahrzeugen."
Flugmedizin Tropenmedizin Reisemedizin 2013, 20(5): 248-254
Harth, K., Kornek, U., Trittel, T., Strachauer, U., Höme, S., Will, K., Stannarius, R. "Granular Gases of Rod-Shaped Grains in Microgravity."
Phys. Rev. Lett. 2013, 110, 144102
Harth, K., Trittel,T., Kornek, U., Höme, S., Will, K., Strachauer, U., Stannarius, R. "Microgravity experiments on a granular gas of elongated grains"
AIP Conf. Proc. 2013, 1542, 807
Paulsen, K., Tauber, S., Gölz, N., Simmet, D.M., Engeli, S., Birlem, M., Dumrese, C., Karer, A., Hunziker, S., Biskup, J., Suh, D., Hürlimann, E., Signer, C., Wang, A., Sang, C., Grote, K.-H., Zhuang, F., Ullrich, O. "Severe disruption of the cytoskeleton and immunologically relevant surface molecules in a human macrophageal cell line in microgravity ? Results of an in vitro experiment on board of the Shenzhou-8 space mission." Acta Astronautica, 2014, 94(1), 277-292
